Tetrahedron Letters p. 543 - 546 (1989)
Update date:2022-08-04
Topics:
Grandas, Ana
Marshall, William S.
Nielsen, John
Caruthers, Marvin H.
Deoxydicytidine phosphoramidite, 4-chlorobenzylmercaptan and tetrazole reacted to form dinucleoside thiophosphite.Oxidation with sulfur yields phosphorodithioates which used to synthesize pentadecadeoxyoligonucleotides containing nuclease resistant phosphorodithioate internucleotide linkages.
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Doi:10.1021/ja9616241
(1996)Doi:10.1080/10426500802590038
(2009)Doi:10.1021/ja00196a043
(1989)Doi:10.1039/b919606d
(2010)Doi:10.1039/c6nj04078k
(2017)Doi:10.1016/j.orgel.2019.105498
(2020)
