Tetrahedron Letters p. 5801 - 5804 (1988)
Update date:2022-08-05
Topics:
Fairhurst, Robin A.
Heaney, Harry
Papageorgiou, George
Wilkins, Robert F.
Regioselectivity in the ortho-dialkylaminomethylation of phenols in greatest, for example in reactions of 2,5-dimethylphenol, when a mixture of the phenol and sulphur dioxide is allowed to stand for several hours before the addition of a bis-(dialkylamino)methane (aminal) or an alkoxydialkylaminomethane (aminol ether).
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