Asymmetric Synthesis of (3R,5R)- and (3S,5S)-2,6-Dimethylheptane-3,5-diol, useful C2 Chiral Auxiliaries

Article abstract of DOI:10.1016/0957-4166(95)00071-V

(R,R)- and (S,S)-2,6-Dimethylheptane-3,5-diol, which are useful C2 chiral auxiliaries, have been both synthesized in high optical purity from 2,6-dimethylheptane-3,5-dione, by using as key step a Sharpless kinetic resolution.