REGIOSELECTIVE SYNTHESIS OF ISOPROPENYL ESTERS BY RUTHENIUM CATALYSED ADDITION OF N-PROTECTED AMINO-ACIDS TO PROPINE

Article abstract of DOI:10.1016/S0040-4039(00)82869-5

A general route to isopropenyl esters of N-protected amino-acids is reported, by direct addition of Z-N or Boc-N amino acids to propyne catalysed by ruthenium(II) complexes; it takes place without racemization.The isopropenyl esters are activated towards