STEREOSELECTIVE SYNTHESES OF γ-HYDROXY-α,β-UNSATURATED ESTERS: AN ASYMMETRIC VERSION OF THE "SPAC" REACTION

Article abstract of DOI:10.1016/S0040-4039(00)99351-1

Double diastereoselection in the Sulfoxide Piperidine And Carbonyl (SPAC) reactions of sulfinyl acetate esters (2) with α-unsubstituted aldehydes (3) has been investigated to facilitate asymmetric syntheses of γ-hydroxy-α,β-unsaturated esters (1).