Synthesis p. 173 - 175 (1994)
Update date:2022-08-02
Topics:
Kishikawa
Eida
Kohmoto
Yamamoto
Yamada
Two methods for the chemoselective alcoholysis of acylureas were developed to generate esters and amides, respectively. In alcoholysis using sodium methoxide in methanol, methoxide attacked the acyl carbonyl to give the corresponding methyl ester. While in alcoholysis using lithium benzyloxide in diethyl ether, benzyloxide attacked the urea carbonyl to give the amide. The chemoselectivity originates in the different chelating abilities of the metals and the polarity of the solvents.
View MoreZhangjiagang Jianing Import & Export Co.,Ltd.
Contact:086-512-55379012 13913607595
Address:NO.1 Guotai North Road Zhangjiagang Economic Development Zone,215600,Jiangsu,China
Contact:+86-021-58123769
Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
Contact:21-7631221 15884421033
Address:326 Science and technology,Shanghai,China
Jiangsu Taihu New Materials Holding Co., Ltd
Contact:+86-519-86160108
Address:Xueyan Town, Changzhou City, Jiangsu Province, 213169, China
Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)
website:http://www.bjgreenchem.com/
Contact:+86-427-6515887
Address:301,302, 3rd Floor, Building C-7, Dongsheng Science Park, Northern Territory, Zhongguancun, No. 66, Xixiaokou Road, Haidian District, Beijing
Doi:10.1016/j.tetlet.2010.01.019
(2010)Doi:10.1016/j.tetlet.2013.03.034
(2013)Doi:10.1016/j.bmcl.2010.02.003
(2010)Doi:10.1002/mrc.2568
(2010)Doi:10.1016/0008-6215(89)84034-0
(1989)Doi:10.1016/j.polymer.2010.01.039
(2010)
