Journal of Organic Chemistry p. 3963 - 3972 (1989)
Update date:2022-08-02
Topics:
Baek, Du-Jong
Daniels, Scott B.
Reed, Peter E.
Katzenellenbogen, John A.
To study the enantioselectivity of alternate substrate inhibition of chymotrypsin by chiral α- and β-arylsubstituted enol lactones, we have prepared four of these lactones in homochiral form: 3-phenyl-6-methylenetetrahydro-2-pyranone (αPh6H, IIa), 3-(1-na
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