Tetrahedron Letters p. 321 - 324 (1989)
Update date:2022-08-03
Topics:
Famulok, Michael
Bosold, Ferdinand
Boche, Gernot
In this communication we describe (1) the synthesis of N-acetoxy-2-aminonaphtaline 4a (an ultimate carcinogen of the carcinogenic 2-naphtylamine), of N-pivaloyloxy-2-aminonaphtaline 4b, and (2) the reactions of 4a(b) with the nucleophiles N-methylaniline 6 and deoxyguanosine 7.Of special interest is the formation of the deoxyguanosine "adducts" 12-14.
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