First preparation of mitomycins specifically labeled with deuterium at the C6-methyl position

DOI: 10.1021/jo00295a051

Source and publish data:

Journal of Organic Chemistry p. 2515 - 2518 (1990)

Update date:2022-09-26

Topics:

Authors:

Kanda Kanda

Kasai Kasai

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00295a051

The C⁶-methyl group of mitomycins was specifically labeled with deuterium. 7,7-(Ethylenedioxy)mitomycin (8), a masked quinonoid compound derived from mitomycin A (2), played an important role in this methodology.

Full text of DOI:10.1021/jo00295a051

Products guided by the article

Product name:1a-acetyl-7-demethoxy-6,7-dihydro-7,7-(ethylenedioxy)-6-(phenylselenyl)mitomycin A

Cas No:122675-60-9

R&D Labs maybe for 122675-60-9

Shanghai Sunwise Chemical Co., Ltd

website:http://www.sunwisechem.com

Contact:86-021-33883180

Address:Room 10E, Building G, Westlink Center, No. 2337 Gudai Road, Minhang District, Shanghai, China PC: 201100
Wuhan Benjamin Pharmaceutical Chemical Co.,Ltd

Contact:86-27-52341789

Address:Room 1518 B suite, optical valley time square, No 111 Guanshan Road, Hongshan District,Wuhan,Hubei Province,China.
Beijing ZhongDaXinHe Chemical Product Co.,Ltd(expird)

Contact:010-52876516

Address:tongzhoubeiyuan
Hubei Lingsheng Pharmaceuticals Co., Ltd.

Contact:+86-0710-3538058

Address:Xiangyang City Xiangcheng Economic Development Zone, Hubei Province
Tianjin Jiuri New Materials Co., Ltd.

Contact:+86-22-58889220

Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.

Relevant to this article

Intriguing substrate tolerance of epoxide hydrolase Lsd19 involved in biosynthesis of the ionophore antibiotic lasalocid A

Doi:10.1021/ol100541e
(2010)
Squaramide-catalyzed enantioselective Friedel-Crafts reaction of indoles with imines

Doi:10.1039/b922120d
(2010)
A concise formal synthesis of diazonamide a by the stereoselective construction of the C10 quaternary center

Doi:10.1002/anie.200906318
(2010)
An enantioselective formal synthesis of (+)-lactacystin from hydroxymethyl glutamic acid (HMG)

Doi:10.1055/s-0029-1219207
(2010)
Synthesis of porous polymeric metalloporphyrins for highly efficient oxidation of cyclohexane in heterogeneous systems

Doi:10.1039/c7nj00564d
(2017)
Multiple-organocatalyst-promoted cascade reaction: A fast and efficient entry into fully substituted piperidines

Doi:10.1002/chem.201000059
(2010)

Article Doi