A Facile One-Pot Procedure for the Synthesis of 1,2-Benzisothiazole 1,1-Dioxides

Article abstract of DOI:10.1055/s-1989-27263

ortho-Lithiated N,N-diphenylbenzenesulfonamides 6 react with aromatic nitriles and N,N-dimethylcarbamonitrile, respectively, to give directly the corresponding 3-substituted 1,2-benzisothiazole-1,1-dioxides 8a-f.Other cyano compounds only transfer the cyano group or its ligands to generate the o-substituted benzenesulfonamides 9a-d.