Magnesium Ion Assisted Highly Regio- and Chemoselective Reduction of 5H-Pyrrolopyridine-5,7(6H)-diones with Sodium Borohydride. A Convenient Synthesis of 6,7-Dihydro-7-hydroxy-5H-pyrrolopyridin-5-ones

DOI: 10.1246/bcsj.62.1205

Source and publish data:

Bulletin of the Chemical Society of Japan p. 1205 - 1210 (1989)

Update date:2022-08-05

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Authors:

Goto, Takehiko

Konno, Michio

Saito, Minoru

Sato, Ryu

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Article abstract of DOI:10.1246/bcsj.62.1205

6-Substituted and unsubstituted 6,7-dihydro-7-hydroxy-5H-pyrrolo<3,4-b>pyridin-5-ones were predominantly obtained in excellent yield by the reduction of the corresponding 5,7-diones with sodium borohydride in the presence of Mg ion at 0 deg C.The highly r

Full text of DOI:10.1246/bcsj.62.1205

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Product name:7-Hydroxy-6-p-tolyl-6,7-dihydro-pyrrolo[3,4-b]pyridin-5-one

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