Stereochemistry of the Michael Addition of Ester and Ketone Enolates to α,β-Unsaturated Ketones

DOI: 10.1021/jo00288a028

Source and publish data:

Journal of Organic Chemistry p. 157 - 172 (1990)

Update date:2022-07-29

Topics:

Authors:

Oare, David A.

Heathcock, Clayton H.

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Article abstract of DOI:10.1021/jo00288a028

The stereo- and regiochemistry of addition of the enolates of ketones and esters to α,β-unsaturated ketones has been studied.There is a strong correlation between the enolate geometry and adduct stereostructure, with E enolates forming syn products and Z

Full text of DOI:10.1021/jo00288a028

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