Synthesis and Synthetic Utility of 1-Acyl-5-(trialkylsilyl)-1,2-dihydropyridines. Synthesis of (+/-)-Elaeokanine A

Article abstract of DOI:10.1021/jo00288a049

The regioselective addition of Grignard reagents to the phenoxycarbonyl salts of 3-(trialkylsilyl)pyridines was studied.Most of the 3-(trialkylsilyl)pyridine salts gave a mixture of dihydropyridines on reaction with aliphatic Grignard reagents.However, al