Journal of Organometallic Chemistry p. 289 - 296 (1994)
Update date:2022-08-05
Topics: Cyclization Palladium-catalysed 2-alkynylanilines 2-substituted indoles
Cacchi, Sandro
Carnicelli, Veronica
Marinelli, Fabio
The cyclization of 2-alkynylanilines in the presence of PdCl2 and n-Bu4NCl under an acidic CH2Cl2-HCl two-phase system affords 2-substituted indoles in good to high yield, at room temperature.The reaction is particularly suited to the one-flask preparatio
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