Application of dibutyltin oxide method to regioselective acylation and alkylation of tylosin at C-4''.

DOI: 10.1248/cpb.37.861

Source and publish data:

Chemical and pharmaceutical bulletin p. 861 - 865 (1989)

Update date:2022-09-26

Topics:

Authors:

Kiyoshima

Sakamoto

Ishikura

Fukagawa

Yoshioka

Naganawa

Sawa Sawa

Takeuchi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.37.861

4''-O-Acyl-, 4''-O-alkyl- and 4''-deoxy-tylosin derivatives were synthesized using 2'-O-acetyl-3'',4''-O-(dibutyl-stannio)tylosin as a synthetic intermediate. The in vitro biological evaluation showed that the new derivatives were active against macrolide-resistant clinical isolates of bacteria and mycoplasmas, and that they were resistant to hepatic esterase.

Full text of DOI:10.1248/cpb.37.861

NII-Electronic Library Service

Products guided by the article

Product name:2'-O-acetyl-4-O-(4-methoxyphenacyl)tylosin

Cas No:124667-89-6

R&D Labs maybe for 124667-89-6

Longhui qunfeng Chemical Co., Ltd

Contact:86-731-82173407

Address:South-east Industrial Park, Longhui County, Hunan Province, China
Guangzhou Chemical Reagent Factory

Contact:+86-20-8435 9820 or 8435 7345

Address:Southern Guangzhou, Guangdong, China
BioBioPha Co., Ltd

Contact:+86-871-65217109

Address:132 Lanhei Road, Kunming Institute of Botany, Chinese Academy of Sciences
SPE Chemicals Co.,Ltd

Contact:

Address:ROOM 1715, No#345 Jin Xiang Road, Pudong District
Wuhan Pengo Technology.,Ltd.

Contact:+86-27-67841589

Address:Add: 999 Gaoxin Road, Donghu New Technology Development Zone, Wuhan City, Hubei, China

Relevant to this article

Design, synthesis and herbicidal activity of 5-cyclopropyl-N-phenylisoxazole-4-carboxamides

Doi:10.1016/j.molstruc.2020.128628
(2020)
Chromium(II) Complexes of o-Phenylenediamine. The Crystal and Molecular Structures of Bis(o-phenylenediamine-κN)bis(thiocyanato-κN)chromium(II) and Bis(o-phenylenediamine-κ²N,N')bis(o-phenylenediamine-κN)chromium(II) Trifluoromethanesulphonate

Doi:10.1039/DT9910002045
(1991)
SYNTHESIS OF EARTHY-MOULDY SMELLING COMPOUNDS-I STEREOSELECTIVE SYNTHESIS OF (+/-)-GEOSMIN

Doi:10.1016/S0040-4039(00)99122-6
(1989)
Iptycenes with an acridinone motif developed through [4+2] cycloaddition of tethered naphthalene and iminoquinone: Via a radical reaction

Doi:10.1039/c7cc03030d
(2017)
New phosphane based on a β-cyclodextrin, exhibiting a solvent-tunable conformation, and its catalytic properties

Doi:10.1002/chem.201000379
(2010)
Multicomponent synthesis of pyridazine and pyridazinoquinazoline derivatives in the presence of catalysts such as magnesium oxide (MgO) and 12-tungstophosphoric acid (PW)

Doi:10.1002/jhet.355
(2011)

Article Doi