Synthesis and biological activity of D3-trishomocubyl-4-amines

Article abstract of DOI:10.1021/jm00106a053

The D₃-trishomocubyl system was prepared from tertiary pentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecan-8-ols 5 in one step by using a modified Ritter reaction yielding only one of the possible two geometrical isomers of 4-amino-3-alkyl (or aryl)