Synthesis of β-lactams via cycloaddition of hydrazones with phenoxyketene

DOI: 10.1021/jo00294a040

Source and publish data:

Journal of Organic Chemistry p. 2196 - 2200 (1990)

Update date:2022-07-29

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Authors:

Sharma Sharma

Pandhi Pandhi

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Article abstract of DOI:10.1021/jo00294a040

Phenoxyketene is capable of annelating the disubstituted hydrazones to afford stereoselectivity cis-monocyclic β-lactams with a 1-amino functionality. The ease of cycloaddition is governed by substitutents on the azomethine carbon as well as on the hydraz

Full text of DOI:10.1021/jo00294a040

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