Fine-tuning the π-π Aromatic interactions in peptides: Somatostatin analogues containing mesityl alanine

DOI: 10.1002/anie.201106406

Source and publish data:

Angewandte Chemie - International Edition p. 1820 - 1825 (2012)

Update date:2022-08-05

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Authors:

Martin-Gago, Pablo

Gomez-Caminals, Marc

Ramon, Rosario

Verdaguer, Xavier

Martin-Malpartida, Pau

Aragon, Eric

Fernandez-Carneado, Jimena

Ponsati, Berta

Lopez-Ruiz, Pilar

Cortes, Maria Alicia

Colas, Begona

MacIas, Maria J.

Riera, Antoni

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Article abstract of DOI:10.1002/anie.201106406

Going through the motions: Somatostatin analogues having greater conformational rigidity than somatostatin have been prepared by substituting Phe residues in the native sequence with mesityl alanine (Msa; see structure). The analogues show high affinity f

Full text of DOI:10.1002/anie.201106406

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