Synthesis of Bis(oxazoline) Ligands Possessing C-5 gem-Disubstitution and Their Application in Asymmetric Friedel-Crafts Alkylations

DOI: 10.1021/acs.joc.5b01767

Source and publish data:

Journal of Organic Chemistry p. 10177 - 10186 (2015)

Update date:2022-08-03

Topics:

Authors:

O'Reilly, Steven

Aylward, Miriam

Keogh-Hansen, Caoimhe

Fitzpatrick, Brian

McManus, Helen A.

Müller-Bunz, Helge

Guiry, Patrick J.

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Article abstract of DOI:10.1021/acs.joc.5b01767

A series of eight novel bis(oxazoline) ligands incorporating gem-disubstitution on one of the oxazoline rings were prepared from (S)-valine. These ligands are designed as a cost-effective alternative to similar ligands possessing an oxazolinyl C(5)-tert-b

Full text of DOI:10.1021/acs.joc.5b01767

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Product name:(S)-2-(2-bromophenyl)-4-isopropyl-5,5-diphenyl-4,5-dihydrooxazole

Cas No:1255859-76-7

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