Tetrahedron p. 11681 - 11692 (1995)
Update date:2022-08-03
Topics:
Shinokubo, Hiroshi
Miki, Hiroaki
Yokoo, Toshiaki
Oshima, Koichiro
Utimoto, Kiitiro
Stereospecific lithium-halogen exchange of alkenyl iodides was performed upon treatment with butyllithium in non-polar solvents such as hexane, benzene, and toluene at 25 deg C to provide alkenylllithiums quantitatively with retention of the configuration.Metal-iodine ecxhange of allenyl iodides with n-BuLi, i-PrMgBr or Et2Zn was also performed effectively to afford the corresponding allenylmetallic reagents.An addition of carbonyl compounds to the metallic reagents gave homopropargylic alcohols with high regioselectivity in good yields.
View MoreNanjing lanbai chemical Co.,Ltd.
Contact:+86-25-85499326
Address:Room 908, 9F Taiyue Building,No.285 Heyan Road
Contact:86-21-57725962
Address:shanghai
MS( MAOSHENG )Chemical CO.,LTD
Contact:+86-519-82726678.82726378
Address:TAOXI INDUSTRY ZONE JINTAN
Yurui(Shanghai)Chemical Co.,Ltd
Contact:0086 21-50456736
Address:No.3188 Xiupu Road,Shanghai
Jiangsu King Road New Materials Co., Ltd.
website:http://www.jskingroad.com
Contact:0519-85720726 0519-85720721 13584535752
Address:No.1,Weihua Road,Xinbei District,Changzhou City,Jiangsu Province
Doi:10.1016/j.bmcl.2010.05.084
(2010)Doi:10.1021/ml100228m
(2011)Doi:10.1016/S0040-4039(00)99257-8
(1989)Doi:10.1016/S0040-4020(01)89077-3
(1989)Doi:10.1021/ol5021256
(2014)Doi:10.1016/j.tetlet.2010.08.100
(2010)