Journal of Medicinal Chemistry p. 1413 - 1418 (1990)
Update date:2022-07-30
Topics:
Goldmann, Siegfried
Born, Liborius
Kazda, Stanislav
Pittel, Bernd
Schramm, Matthias
4,4-Disubstituted 1,4-dihydropyridines are synthesized by intramolecular addition of sulfinyl carbanions to pyridines.These disubstituted derivatives show a loss of Ca antagonistic potency of up to three powers of 10 both in vitro on aortic rings and in v
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