
Tetrahedron Letters p. 2117 - 2120 (1989)
Update date:2022-07-30
Topics:
Hotoda, Hitoshi
Ueno, Yoshihito
Sekine, Mitsuo
Hata, Tsujiaki
A dinucleotide dipeptide (H-Ala-Tyr-(pUpU)-OH) was synthesized via a phosphorothioate triester intermediate (1).It was found that the P-S bond was selectively cleaved by the use of (n-Bu3Sn)2O without undesired dephosphorylation of tyrosine.
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(1955)