Synthesis of isochromans by hydriodic acid or iodine mediated cyclization reactions of 1-(2-vinylphenyl)propan-2-ols

Article abstract of DOI:10.3987/COM-10-12021

Treatment of 1-(2-vinylphenyl)propan-2-ols, which can be easily prepared from 2-bromostyrenes and epoxides, with hydriodic acid in acetonitrile yields the corresponding isochromans (1H-3,4-dihydro-2-benzopyrans). When the above alcohols are treated with i