Tetrahedron Letters p. 123 - 124 (1995)
Update date:2022-08-05
Topics:
Fronza, Giovanni
Fogliato, Giovanni
Fuganti, Claudio
Lanati, Simonetta
Rallo, Roberta
Servi, Stefano
Baker's yeast reduction of benzylidene cyclohexanone 1 affords, as major transformation product, enantiomerically pure (S) carbinol 3, yielding in two steps (2S) 2-acetoxycyclohexanone 6, close to nearly racemic saturated ketone 4, whereas carbinol 5 and its enantiomer 8 can be obtained from 3 upon LiAlH4 reduction upon baker's yeast reduction to 7, followed by inversion of configuration, respectively. - Keywords: baker's yeast, reduction, enantioselectivity, diastereoselectivity
View MoreContact:86 513 85512619
Address:Rm.1306, Building A, Wenfeng Mansion,168 Gongnong Road, Nantong Jiangsu China
Hangzhou LINGEBA Technology Co., Ltd.
Contact:+0086-571-87389059
Address:Office 1-913,NewYouth Plaza, GongShu Area, HangZhou,ZheJiang,P.R.China
Contact:+86-731-84427351
Address:154 JIANXIANG SOUTH ROAD
Shanghai AoBo Bio-Pharmaceutical Technology Co., Ltd.
Contact:+86-21-51320130-801, 816
Address:Room 601, No. 1011, Halei Road, Zhangjiang High-Tech Park, Pudong, Shanghai
Contact:+86-27-85733560
Address:NO.308,QINGNIAN RD.,WUHAN,CHINA
Doi:10.1055/s-0030-1258211
(2010)Doi:10.1016/j.tetlet.2010.10.020
(2010)Doi:10.1016/S0040-4039(00)99302-X
(1989)Doi:10.1021/om00118a086
(1990)Doi:10.3762/bjoc.5.73
(2009)Doi:10.1021/om100671s
(2011)
