125992-54-3Relevant academic research and scientific papers
On the Mode of Baker's Yeast Reduction of Benzylidenecyclohexanone
Fronza, Giovanni,Fogliato, Giovanni,Fuganti, Claudio,Lanati, Simonetta,Rallo, Roberta,Servi, Stefano
, p. 123 - 124 (1995)
Baker's yeast reduction of benzylidene cyclohexanone 1 affords, as major transformation product, enantiomerically pure (S) carbinol 3, yielding in two steps (2S) 2-acetoxycyclohexanone 6, close to nearly racemic saturated ketone 4, whereas carbinol 5 and its enantiomer 8 can be obtained from 3 upon LiAlH4 reduction upon baker's yeast reduction to 7, followed by inversion of configuration, respectively. - Keywords: baker's yeast, reduction, enantioselectivity, diastereoselectivity
Enzymic Preparation of Enantiomerically Pure Cyclohexanols: Ester Synthesis by Irreversible Acyl Transfer
Laumen, Kurt,Seemayer, Robert,Schneider, Manfred P.
, p. 49 - 51 (2007/10/02)
Enantiomerically pure cyclohexanols are prepared enzymically via irreversible acyl transfer; they are valuable substitutes for 8-phenylmenthols and are potentially useful as chiral auxiliaries.
