Bioorganic and Medicinal Chemistry Letters p. 6978 - 6982 (2010)
Update date:2022-07-29
Topics:
Wu, Tom Y.H.
Juteau, Hélne
Ducharme, Yves
Friesen, Richard W.
Guiral, Sébastien
Dufresne, Lynn
Poirier, Hugo
Salem, Myriam
Riendeau, Denis
Mancini, Joseph
Brideau, Christine
Microsomal prostaglandin E2 synthase (mPGES-1) represents a potential target for novel analgesic and anti-inflammatory agents. High-throughput screening identified several leads of mPGES-1 inhibitors which were further optimized for potency and
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