REGIOSELECTIVE SYNTHESIS OF EITHER α- OR γ-AMINO ACID DERIVATIVES VIA Li, Sn-MASKED, AND/OR Ge-MASKED DIENOLATES

Article abstract of DOI:10.1016/S0040-4039(00)99268-2

Either the α- (3) or γ-amino acid derivatives (4) can be prepared with very high regioselectivity by treating diethyl azodicarboxylate (DEAD) with (i) lithium dienolates themselves (2) in certain cases, (ii) Sn-masked dienolates (5), or (iii) Ge-masked di