Tetrahedron Letters p. 3393 - 3396 (1989)
Update date:2022-07-29
Topics:
Poindexter, Graham S.
Foley, Michael A.
Licause, Joseph F.
4-Aryl-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic esters are metalated at the NH and the C-2 methyl positions via treatment with two equivalents of n-butyl lithium.The resulting dilithio species can be treated with a variety of electrophiles to fur
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