Cyclic hexapeptides and chimeric peptides as mimics of tendamistat

DOI: 10.1021/ja00102a008

Source and publish data:

Journal of the American Chemical Society p. 10412 - 10425 (1994)

Update date:2022-07-29

Topics:

Authors:

Etzkorn, Felicia A.

Guo, Tao

Lipton, Mark A.

Goldberg, Steven D.

Bartlett, Paul A.

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Article abstract of DOI:10.1021/ja00102a008

We describe the design and evaluation of structural mimics of tendamistat, a 74-residue proteinaceous inhibitor of α-amylase. Cyclic hexapeptides were designed in which the sequence Trp-Arg-Tyr is constrained to the i + 1 to i + 3 positions of a type I β-

Full text of DOI:10.1021/ja00102a008

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