
Journal of the American Chemical Society p. 10412 - 10425 (1994)
Update date:2022-07-29
Topics:
Etzkorn, Felicia A.
Guo, Tao
Lipton, Mark A.
Goldberg, Steven D.
Bartlett, Paul A.
We describe the design and evaluation of structural mimics of tendamistat, a 74-residue proteinaceous inhibitor of α-amylase. Cyclic hexapeptides were designed in which the sequence Trp-Arg-Tyr is constrained to the i + 1 to i + 3 positions of a type I β-
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