Chelating ligands functionalized for facile attachment to biomolecules. A convenient route to 4-isothiocyanatobenzyl derivatives of diethylenetriaminepentaacetic acid and ethylenediaminetetraacetic acid

DOI: 10.1021/jo00296a057

Source and publish data:

Journal of Organic Chemistry p. 2868 - 2871 (1990)

Update date:2022-07-29

Topics:

Authors:

Keana Keana

Mann Mann

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Article abstract of DOI:10.1021/jo00296a057

The title compounds were synthesized by alkylation of the monoenolates of DTPA and EDTA permethyl esters 3 and 4 with benzyl bromide. The benzylated esters 5 and 6 were nitrated, hydrogenated, and converted to their isothiocyanate derivatives 13 and 14 in

Full text of DOI:10.1021/jo00296a057

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