α-Lithioamine Synthetic Equivalents: Syntheses of Diastereoisomers from the Boc Piperidines

DOI: 10.1021/jo00296a008

Source and publish data:

Journal of Organic Chemistry p. 2578 - 2580 (1990)

Update date:2022-08-04

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Authors:

Beak, Peter

Lee, Won Koo

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Article abstract of DOI:10.1021/jo00296a008

The α'-lithiations and electrophilic substitutions of selected Boc piperidines provide single or separable diastereoisomeric 2-substituted, 2,4-disubstituted, and 2,4,6-trisubstituted Boc piperidines which are readily hydrolyzed to the substituted piperidines.

Full text of DOI:10.1021/jo00296a008

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