Preparation of 3-Substituted 4-Thianones and Their 1,1-Dioxides via Palladium Mediated Deallyloxycarbonylation

Article abstract of DOI:10.1055/s-1989-27389

3-Alkyl-4-thianones 4 (3-alkyl-thiacyclohexan-4-ones) can be conveniently prepared by the alkylation of 3-allyloxycarbonyl-4-thianone (1b) followed by deallyloxycarbonylation mediated by tetrakis(triphenylphospine)palladium in the presence of morpholine.The corresponding sulphones 9, as well as 2,3-dialkyl-4-thianone derivatives 12 and 13 can be prepared by analogous procedures.