Stereocontrolled reductive amination of 3-hydroxy ketones

DOI: 10.1016/S0040-4039(97)01349-X

Source and publish data:

Tetrahedron Letters p. 5981 - 5984 (1997)

Update date:2022-08-03

Topics:

Authors:

Haddad, Mansour

Dorbais, Jerome

Larcheveque, Marc

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Article abstract of DOI:10.1016/S0040-4039(97)01349-X

syn-1,3-Aminoalcohols are synthesized in high diastereomeric excess by reductive amination of 3-hydroxyketones with sodium cyanoborohydride in the presence of benzylamine.

Full text of DOI:10.1016/S0040-4039(97)01349-X

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