
Tetrahedron Letters p. 5361 - 5364 (1989)
Update date:2022-08-02
Topics:
Jones, Raymond C. F.
Hirst, Simon C.
The enaminoester 1-benzyl-2-ethoxycarbonylmethyleneimidazolidine reacts with α,β-enones and other Michael acceptors to give 1,4-adducts; removal of the ethoxycarbonyl group completes overall conjugate addition of the imidazoline α-anion (which itself adds 1,2 to enones),and hydrolysis affords carboxylic acids.
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