Triazole antifungals. IV. Synthesis and antifungal activities of 3-acylamino-2-aryl-2-butanol derivatives

DOI: 10.1248/cpb.39.2581

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2581 - 2589 (1991)

Update date:2022-08-02

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Authors:

Konosu Konosu

Tajima Tajima

Takeda Takeda

Miyaoka Miyaoka

Kasahara

Yasuda Yasuda

Oida Oida

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Article abstract of DOI:10.1248/cpb.39.2581

New triazole compounds were designed and synthesized as potential inhibitors of the fungal cytochrome P-450 14α-demethylase. In testing for antifungal activity against a mouse systemic Candida albicans infection, (2R,3R)3-acylamino-2-aryl-2-butanol deriva

Full text of DOI:10.1248/cpb.39.2581

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