Journal of Medicinal Chemistry p. 1721 - 1728 (1990)
Update date:2022-08-04
Topics:
Jiang, J. B.
Hesson, D. P.
Dusak, B. A.
Dexter, D. L.
Kang, G. J.
Hamel, E.
A novel series of 2-styrylquinazolin-4(3H)-ones which inhibited tubulin polymerization and the growth of L1210 murine leukemia cells was discovered.Extensive structure-activity relationship studies suggest that the entire quinazolinone structure was requi
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