Novel aryloxy azolyl chalcones with potent activity against Mycobacterium tuberculosis H37Rv

DOI: 10.1016/j.ejmech.2011.06.037

Source and publish data:

European Journal of Medicinal Chemistry p. 4302 - 4310 (2011)

Update date:2022-07-29

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Authors:

Marrapu, Vijay K.

Chaturvedi, Vinita

Singh, Shubhra

Singh, Shyam

Sinha, Sudhir

Bhandari, Kalpana

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Article abstract of DOI:10.1016/j.ejmech.2011.06.037

A series of twenty seven novel aryloxy azolyl chalcones were synthesized and evaluated in vitro for the growth inhibition of Mycobacterium tuberculosis H37Rv. Ten compounds from this series exhibited good activity with MIC in the range of 3.12-0.78 μg/mL

Full text of DOI:10.1016/j.ejmech.2011.06.037

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