General Synthesis of 2-, 3-, and 4-Hydroxyalkylphosphonium Salts by the Reaction of Triphenylphosphine with Cyclic Ethers in the Presence of Strong Acids.

Article abstract of DOI:10.1246/bcsj.61.4476

Cyclic ethers were efficiently converted to the corresponding hydroxyalkylphosphonium salts by the reaction with triphenylphosphine and trifluoromethanesulfonic or trifluoroacetic acid.The reaction of these salts with bases afforded the corresponding phos