DIFFERENT REACTIVITIES OF ACETYLATED exo- AND endo-CYANOETHYLIDENE DERIVATIVES IN GLYCOSYLATION REACTIONS

Article abstract of DOI:10.1016/0008-6215(89)85016-5

The condensation of acetylated 1-(endo-cyano)ethylidene derivatives having the D-gluco, D-xylo, and D-galacto configurations (2-6) with a primary (8) and a secondary (9) trityl derivative was more rapid than for the corrensponding exo-isomers.This difference in reactivity is explained on the basis of differences in conformation.