Tetrahedron p. 7353 - 7360 (1989)
Update date:2022-07-30
Topics: Synthesis Enantiomer Catalyst Stereochemistry Chromatography Reactant Pyrethroid
Yadav, J. S.
Mysorekar, Sudha V.
Rao, A. V. Rama
A synthesis of (1R)-(+)-cis-chrysanthemic acid from (R,R)-tartaric acid is described.The diol 8 was converted to the mono MEM protected compound 8b.Dehydration of the tertiary alcohol using methanesulfonyl chloride-triethylamine-DMAP and treatment of the resulting product with lithium in liquid ammonia afforded 10.The diazoester of 10 was subjected to intramolecular cyclopropanation using a soluble copper complex to obtain 12.Cleavage of the MEM ether, dehydration of the tertiary alcohol followed by reductive cleavage with lithium in liquid ammonia gave the title compound.
View MoreShanghai Yuanye Bio-Technology Co., Ltd.
website:http://www.shyuanye.com
Contact:+86-21-61845781
Address:Building 6, No. 465, Changta Road,Songjiang District,Shanghai,China
YingYing Pharmaceutical Co.,Ltd
Contact:86-18854126208
Address:55#, yingxiongshan road
Yingkou Sanzheng New Technology Chemical Industry Co., Ltd.
Contact:+86-417-2927806
Address:yingkou
Ji'nan Orgachem Pharmaceutical Co.,Ltd
Contact:+86-531-82687810
Address:Jinan
Feis International Trade Co,. Ltd
Contact:13961823444-18235944442
Address:Wuxi jiangsu
Doi:10.1016/j.tet.2011.01.066
(2011)Doi:10.1021/ic200143b
(2011)Doi:10.1248/cpb.40.2377
(1992)Doi:10.1016/j.bioorg.2018.07.009
(2018)Doi:10.1016/j.tetlet.2011.01.043
(2011)Doi:10.1016/0008-6215(89)85099-2
(1989)
