The synthesis of amidine derivatives of imidazoline nitroxides - A new series of pH-sensitive spin probes and labels

Article abstract of DOI:10.1055/s-1992-26343

A synthesis of amidine derivatives, 4-alkyl[aryl]amino-2,5-dihydro-2,2,5,5-tetramethylimidazol-1-yl oxides is described. The first step is a 1,3-dipolar cycloaddition of 2,5-dihydro-2,2,5,5-tetramethylimidazol-1-yl 1,3-dioxide with isocyanates or diisocya