Tetrahedron Letters p. 307 - 310 (1990)
Update date:2022-08-05
Topics:
Kende, Andrew S.
DeVita, Robert J.
The four-carbon homologation of aldehydes to E,E-dienamines can be achieved efficiently under mild conditions by iodomethylenation with CrCl2-CHI3, with subsequent Pd-catalyzed coupling to the vinylstannane 4 followed by mild cleavage of the FMOC group.
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