Tetrahedron Letters p. 5421 - 5424 (1989)
Update date:2022-08-04
Topics:
Reetz, M.T.
Schmitz, A.
Holdgruen, X.
N,N-dibenzyl-protected α-amino-aldehydes 1 undergo non-chelation-controlled aldol additions of 1-phenoxy-1-trimethylsiloxyethylene 2 followed by β-lactone formation and dyotropic rearrangement, all three reactions being catalyzed by MgCl2.The products, 4-substituted 3-amino-χ-lactones 3, are stereochemically pure (de and ee > 99percent).
View MoreShanghai Forever Biotech Co., Ltd.
Contact:+86-21-69734790
Address:Room 5017/5019、5022、5024 of Technology Innovation Centre, No.1155, Gongyuan East Rd, QingPu District, Shanghai China.
Suzhou Kangrun Pharmaceutical, Inc
Contact:86-512-63912376，63913329
Address:Building 2, No. 2358 ,Chang'an Rd, Wujiang Economic Development Zone Pioneering park, china
Anhui Asahikasei Chemical Co., Ltd
Contact:86-551-4259770
Address:No. 88 Linquan Road Hefei Anhui China
Tianjin Hedong Red Cliff Chemical Reagent Factory
Contact:+86-022-84780548
Address:Li Ming Zhuang Gong Ye Yuan,Dongli District,Tianjin,China
Shijiazhuang Haotian Chemical Co., Ltd.
Contact:86-311-85044374
Address:293 Donggang Road
Doi:10.1021/jo00028a032
(1992)Doi:10.1166/jnn.2015.10671
(2015)Doi:10.1021/ol200693d
(2011)Doi:10.1039/c0cc04667a
(2011)Doi:10.1002/anie.201007675
(2011)Doi:10.1039/p29960002525
(1996)
