Agents for the treatment of overactive detrusor. I. Synthesis and structure-activity relationships of 1,1'-biphenyl derivatives

DOI: 10.1248/cpb.39.2915

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2915 - 2923 (1991)

Update date:2022-08-05

Topics:

Authors:

Take Take

Okumura Okumura

Takimoto

Kato Kato

Ohtsuka Ohtsuka

Shiokawa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.39.2915

A series of 1,1'-biphenyl-2,6-dicarboxylic acid diesters were synthesized and examined for their inhibitory activity on guinea-pig detrusor muscle contraction at electrical field stimulation in vitro. Among them, 6-isopropyl 2-methyl 3-hydroxy-5-methyl-2'

Full text of DOI:10.1248/cpb.39.2915

NII-Electronic Library Service

Products guided by the article

Product name:3,5-Cyclohexadiene-1,3-dicarboxylic acid, 4-methyl-6-(4-morpholinyl)-2-(2-nitrophenyl)-, 3-(1,1-dimethylethyl) 1-methyl ester

Cas No:127975-57-9

R&D Labs maybe for 127975-57-9

Guangzhou Congen Pharmatec Co.,Ltd.

website:https://www.congenpharma.com

Contact:86-020-82350801

Address:Room 501, Building G11, South China Advanced Materials Innovation Park, 31 Kefeng Road, Science City, Guangzhou, China 510663
Beijing Apis Biotechnology Co., Ltd.

Contact:86-010-67856775-8551

Address:NO.4PUHUANGYU ROAD,FENTAI DISTRICT, BEIJING, CHINA
Frapp's Chemical (NFTZ) Co.,Ltd

Contact:+86-576-86137892

Address:General Chamber of Commercial Building, 159 Wanchang Middle Road, Wenling, Zhejiang, China
BOC Sciences

website:https://www.bocsci.com/

Contact:1-631-485-4226

Address:Ramsey Road
Jinan Great Chemical Co.,Ltd.

Contact:+86-531-58668191 58668193 58668196 58661173

Address:No 55,Beixiaoxinzhuang West Street,Jinan City, Shandong Province

Relevant to this article

Nonactin biosynthesis: The initial committed step is the condensation of acetate (malonate) and succinate

Doi:10.1021/ja016965f
(2002)
Potent and highly selective benzimidazole inhibitors of PI3-kinase delta

Doi:10.1021/jm300717c
(2012)
Michael, Michael-aldol and Michael-Michael reactions of enolate equivalents of butane-2,3-diacetal protected glycolic acid derivatives

Doi:10.1039/b512410g
(2005)
A versatile synthesis of triarylantimony difluorides by fluorination of triarylstibanes with nitrosyl tetrafluoroborate and their antitumor activity

Doi:10.1016/j.jfluchem.2017.04.004
(2017)
Facile and highly enantioselective synthesis of axially chiral biaryls by enzymatic desymmetrization

Doi:10.1055/s-2002-19349
(2002)
Doi:10.1139/v73-239
(1973)

Article Doi