Agents for the treatment of overactive detrusor. I. Synthesis and structure-activity relationships of 1,1'-biphenyl derivatives

DOI: 10.1248/cpb.39.2915

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2915 - 2923 (1991)

Update date:2022-08-05

Topics:

Authors:

Take Take

Okumura Okumura

Takimoto

Kato Kato

Ohtsuka Ohtsuka

Shiokawa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.39.2915

A series of 1,1'-biphenyl-2,6-dicarboxylic acid diesters were synthesized and examined for their inhibitory activity on guinea-pig detrusor muscle contraction at electrical field stimulation in vitro. Among them, 6-isopropyl 2-methyl 3-hydroxy-5-methyl-2'

Full text of DOI:10.1248/cpb.39.2915

NII-Electronic Library Service

Products guided by the article

Product name:3,5-Cyclohexadiene-1,3-dicarboxylic acid, 4-methyl-6-(4-morpholinyl)-2-(2-nitrophenyl)-, 3-(1,1-dimethylethyl) 1-methyl ester

Cas No:127975-57-9

R&D Labs maybe for 127975-57-9

Xi'an HO-SHINE Bio-Technology Co., Ltd

Contact:+86 (29) 8248-5435/18292020086

Address:No.6 Shiyuan Road Xian City Shaanxi Province, 710048 China
Jiangsu Fengshan Group Co., Ltd.

Contact:86-25-86558671

Address:1903,Central International Mansion 105-6 North Zhongshan Road, Nanjing, China
Shanghai Rainbow Chemistry Co., Ltd.

Contact:+86-21-64968086-5815/5812

Address:3rd floor, Building 7, 251 Faladi Road, Zhangjiang Hi-Tech Park, Pudong District, Shanghai, P.R. China
Xinchang Jiu Xin Pharmaceutical Co., Ltd

website:http://www.jiuxinpharm.com

Contact:86 137 5756 8585

Address:Poyang industry Park
Quhua Zhongxing Refrigeration Technology Co.,Ltd.

Contact:+86-5708886618

Address:318 Bulding 2, No.866 Quhua Rd.,Kecheng District

Relevant to this article

Nonactin biosynthesis: The initial committed step is the condensation of acetate (malonate) and succinate

Doi:10.1021/ja016965f
(2002)
Potent and highly selective benzimidazole inhibitors of PI3-kinase delta

Doi:10.1021/jm300717c
(2012)
Michael, Michael-aldol and Michael-Michael reactions of enolate equivalents of butane-2,3-diacetal protected glycolic acid derivatives

Doi:10.1039/b512410g
(2005)
A versatile synthesis of triarylantimony difluorides by fluorination of triarylstibanes with nitrosyl tetrafluoroborate and their antitumor activity

Doi:10.1016/j.jfluchem.2017.04.004
(2017)
Facile and highly enantioselective synthesis of axially chiral biaryls by enzymatic desymmetrization

Doi:10.1055/s-2002-19349
(2002)
Doi:10.1139/v73-239
(1973)

Article Doi