Agents for the treatment of overactive detrusor. I. Synthesis and structure-activity relationships of 1,1'-biphenyl derivatives

DOI: 10.1248/cpb.39.2915

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2915 - 2923 (1991)

Update date:2022-08-05

Topics:

Authors:

Take Take

Okumura Okumura

Takimoto

Kato Kato

Ohtsuka Ohtsuka

Shiokawa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.39.2915

A series of 1,1'-biphenyl-2,6-dicarboxylic acid diesters were synthesized and examined for their inhibitory activity on guinea-pig detrusor muscle contraction at electrical field stimulation in vitro. Among them, 6-isopropyl 2-methyl 3-hydroxy-5-methyl-2'

Full text of DOI:10.1248/cpb.39.2915

NII-Electronic Library Service

Products guided by the article

Product name:3,5-Cyclohexadiene-1,3-dicarboxylic acid, 4-methyl-6-(4-morpholinyl)-2-(2-nitrophenyl)-, 3-(1,1-dimethylethyl) 1-methyl ester

Cas No:127975-57-9

R&D Labs maybe for 127975-57-9

Chengdu ZY Biochemical Technology Co., LTD

Contact:0086-28-88680086

Address:170 Qingpu Road, Shouan Town, Pujiang County
Shanghai Longschem Co.,Ltd

Contact:021-36356756

Address:Room601,Building No.14,280 Yangcheng Road,Shanghai
Xi'an Unique Electronic and Chemical Co., Ltd.

Contact:+86-029-88238008

Address:1703# B BUILDING WEST ELECTRONIC ZONE, XI'AN, CHINA
SINO Industries Company Limited(expird)

Contact:86-29-85369724

Address:No.111, Jiefang Road, Xi’an, China
ZHEJIANG NHU COMPANY LTD.

Contact:86-575-86132822，86-575-86085355

Address:No.418 Dadao West Road,Qixing Street,Xinchang, Zhejiang Province, China.

Relevant to this article

Nonactin biosynthesis: The initial committed step is the condensation of acetate (malonate) and succinate

Doi:10.1021/ja016965f
(2002)
Potent and highly selective benzimidazole inhibitors of PI3-kinase delta

Doi:10.1021/jm300717c
(2012)
Michael, Michael-aldol and Michael-Michael reactions of enolate equivalents of butane-2,3-diacetal protected glycolic acid derivatives

Doi:10.1039/b512410g
(2005)
A versatile synthesis of triarylantimony difluorides by fluorination of triarylstibanes with nitrosyl tetrafluoroborate and their antitumor activity

Doi:10.1016/j.jfluchem.2017.04.004
(2017)
Facile and highly enantioselective synthesis of axially chiral biaryls by enzymatic desymmetrization

Doi:10.1055/s-2002-19349
(2002)
Doi:10.1139/v73-239
(1973)

Article Doi