Addition of Zinc Homoenolates to Acetylenic Esters: A Formal Cycloaddition

DOI: 10.1021/jo00301a003

Source and publish data:

Journal of Organic Chemistry p. 4235 - 4237 (1990)

Update date:2022-08-05

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Authors:

Crimmins, Michael T.

Nantermet, Philippe G.

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Article abstract of DOI:10.1021/jo00301a003

Addition of zinc homoenolates to acetylenic esters results in conjugate addition followed by intramolecular acylation of the intermediate allenolate to produce 2-carbalkoxycyclopentenones, formally a <3+2> cycloaddition, in a single operation.

Full text of DOI:10.1021/jo00301a003

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