EFFICIENT SYNTHESIS OF 1,2-seco AND 1,2-seco 2-nor PYRIMIDINE AND PURINE NUCLEOSIDES.

DOI: 10.1016/S0040-4039(01)93332-5

Source and publish data:

Tetrahedron Letters p. 6165 - 6168 (1989)

Update date:2022-07-29

Topics: Efficient Synthesis Experimental terms Chemical terms Purine nucleosides

Authors:

Azymah, Muhammad

Chavis, Claude

Lucas, Marc

Imbach, Jean-Louis

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(01)93332-5

Unprotected sylilated purines and pyrimidines (adenine, guanine, cytosine, thymine) reacted with acetoxymethyl ether (acyclic sugar analogues) under solid PTC conditions, using KI and dibenzo-18-crown-6 in benzene-acetonitrile(1:1, v/v) to give regiospecifically the corresponding N-9 purine and N-1 pyrimidine acyclic nucleosides in fairly good yields.

Full text of DOI:10.1016/S0040-4039(01)93332-5

Products guided by the article

Product name:C₂₃H₂₁N₅O₅

Cas No:128316-74-5

R&D Labs maybe for 128316-74-5

Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

website:http://www.bjgreenchem.com/

Contact:+86-427-6515887

Address:301,302, 3rd Floor, Building C-7, Dongsheng Science Park, Northern Territory, Zhongguancun, No. 66, Xixiaokou Road, Haidian District, Beijing
Goldwills Pharmaceuticals Co., Ltd.

Contact:0916-2237889 13991621155

Address:North Suburb of Hanzhong city, Shaanxi Province
WUXI KINGHAN BIO-MEDICAL&CHEMICAL INC.

Contact:13861062998

Address:Room 1316,No.1619 Huishan Avenue,Wuxi,China
Henan Harvest Chem Co., Ltd

Contact:+86-371-86058576

Address:NO.32, Jingsan Road, Zhengzhou, China
Airsea(Taizhou) Pharmaceutical Limited(expird)

Contact:+86-576-88057622

Address:Dubei, Duqiao, Linhai, Taizhou, Zhejiang, China Zip: 317016

Relevant to this article

Construction of Hydroxylated Alkaloids (+/-)-Mannonolactam, (+/-)-Deoxymannojirimycin, and (+/-)-Prosopinine through Aza-Annulation

Doi:10.1021/jo00092a015
(1994)
A Method to Accomplish a 1,4-Addition Reaction of Bulky Nucleophiles to Enones and Subsequent Formation of Reactive Enolates

Doi:10.1021/ol010071i
(2001)
Doi:10.1002/hlca.19730560836
(1973)
Doi:10.1021/jo01094a607
(1959)
Arylaminomaleimides as a new class of aggregation-induced emission-active molecules obtained from organoarsenic compounds

Doi:10.1246/cl.2012.1445
(2012)
Novel Schiff bases derived from N-aryl maleimide derivatives as an effective antimicrobial agent: Theoretical and experimental approach

Doi:10.1016/j.bioorg.2020.104129
(2020)

Article Doi