European Journal of Medicinal Chemistry p. 187 - 190 (1990)
Update date:2022-08-05
Topics:
Andreani, Aldo
Rambaldi, Mirella
Locatelli, Alessandre
Bossa, Rosaria
Galatulas, Iraklis
Ninci, Mauro
The paper reports the synthesis of 3-(2,5-dimethoxybenzylidene)- 2 and 3-(4-pyridylmethylene)-2-indolinones 3 which, as expected, proved to have significant positive inotropic activity.On the contrary, 3-(2,5-dimethoxybenzyl)- 4 and 3-(4-pyridylmethyl)-2-indolinones 5, obtained by reduction of the corresponding compounds 2 and 3, were devoid of cardiotonic activity.
View MoreContact:+86-20-32051076
Address:1105,Building A, International Business Incubator,Science City
Tianjin Jiuri New Materials Co., Ltd.
Contact:+86-22-58889220
Address:C-5/6, Vison Hill, No.1 Gonghua Road, Huayuan Hi-tech Park, Tianjin, China.
Chengdu Baishixing Science and Technology Industry Co., Ltd.
website:http://www.cd-bsx.com
Contact:+86-28-88531548
Address:#217,North of Industry Road,Heshan Town,Pujiang County,Chengdu,Sichuan,China.
Contact:+86-571-86025531 / 86024803
Address:1218-24 Guangyin Mansion,42 Fengqi East Road
website:http://www.china-sinoway.com
Contact:+86-592-5853819
Address:16/F,Huicheng Comm,Complex,No839 XiaHe Rd, Xiamen,China
Doi:10.3390/molecules16043168
(2011)Doi:10.1039/c0ob00547a
(2011)Doi:10.1016/j.molstruc.2013.12.060
(2014)Doi:10.1021/jacs.7b13526
(2018)Doi:10.1016/S0040-4039(00)94343-0
(1990)Doi:10.1016/S0040-4039(00)70713-1
(1989)
