Model studies towards the applicability of the readily available (S)-N-tritylaspartic anhydride in the synthesis of amino acids and peptides

Article abstract of DOI:10.1016/0040-4020(94)01114-F

Reactions of N-tritylaspartic acid anhydride, readily available through N,N'-dicyclo-hexylcarbodiimide-mediated dehydration of N-tritylaspartic acid, with Grignard and Wittig reagents, bulky hydrides, and amines or alcohols of the benzhydryl type, lead regioselectively to products from attack at the β-carbonyl function.