Thermal reaction of 5-aryl-6-trifluoromethyl-3,6-dihydro-2H-[1,3,4]oxadiazines accessing 5-trifluoromethylimidazols

DOI: 10.3987/com-07-s(w)12

Source and publish data:

Heterocycles p. 351 - 356 (2007)

Update date:2022-09-26

Topics:

Authors:

Kamitori, Yasuhiro

Sekiyama, Tomoko

Okada, Etsuji

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Article abstract of DOI:10.3987/com-07-s(w)12

Thermal reaction of 5-aryl-6-trifluoromethyl-3,6-dihydro-2H-[1,3,4]oxadiazines (2) readily obtainable from 3-aryl-3-dimethylhydrazono-1,1,1-trifluoro-2-propanones (1) afforded 4-aryl-l-methyl-5-trifluoromethyl-imidazoles (3) in moderate to good yields. Mechanism for this thermal transformation reaction is also discussed.

Full text of DOI:10.3987/com-07-s(w)12

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