threo-Selective Michael Addition of N,N-Dibenzylglycinate and Alaninate Enolates to α,β-Unsaturated Esters. A Concise and Stereoselective Synthesis of (+/-)-CCG-II

Article abstract of DOI:10.1246/cl.1990.377

Lithium enolates of N,N-dibenzylglycinate and alaninate added to β-substituted α,β-unsaturated esters, and threo-adducts were obtained in high stereoselectivities.The reaction was employed in a concise and stereoselective synthesis of (+/-)-CCG-II.